355nm DPSS UV laser etching chip channels

Lab-on-chip or micro-Total Analytical System is a science and technology characterized by the manipulation of fluids in the micron-scale space, and is also the core component of microfluidics. It is mainly used for innovative research in disciplines such as chemistry, fluid mechanics, material science and biomedicine or interdisciplinary research.

The significance of microfluidic chips lies in the fact that with the help of bionic structures and other materials, traditional large laboratories can be "miniatured" on a chip of the order of square centimeters to carry out functions including sampling, dilution, reagent addition, reaction, separation, and detection. , that is, the miniaturization and integration of the laboratory, not only easy to carry, but also reusable, greatly shortening the time. For example, by simulating the physiological functions of tissues and organs through microfluidic chips, it can make up for the shortcomings of traditional cell tissue culture, animal experiments or sample processing. It is an indispensable and important tool in the scientific research process to achieve the maximum utilization efficiency of reagent consumables.

At present, the materials commonly used in the production of microfluidic chips include: silicon wafers, quartz, glass, polymers (including PMMA, PC, COC, PDMS, Flxdym, PP, PS, PET...), among which polymers Due to the advantages of low cost and easy molding, the material has a wide range of applications. The technologies for making polymers into microfluidic chips mainly include mold-based hot pressing method, molding method, injection molding method and direct processing laser etching method. Since the channel size of microfluidic chips ranges from tens of microns to hundreds, the requirements for precision machining systems are relatively high. The hot pressing method, molding method, and injection molding method are mainly used in industrial mass production. The disadvantage is that the production cycle of high-precision molds is long, and they need to be replaced frequently, and the overall cost is high.

Laser etching is a non-contact and high-efficiency processing method. It uses high-energy-density laser beams to form structures on polymers. It has high processing efficiency and small spot diameters. It can achieve micro-sized channel etching and can be modified in real time through software. Design diagrams and parameters, and etching circuits are more flexible and diverse, especially meeting the needs of scientific research, laboratories and other institutions with fast iterative experimental plans and fast response. Nowadays, the commonly used laser micromachining + hot bonding method prepares PMMA chips integrated with filter membranes, laser micromachining + double-sided adhesive bonding method prepares COC chips and multi-layer flexible PET chips, and laser micromachining method processes crosses on PMMA substrates. Channel + sealing channel and through-hole array structure after bonding, etc.

S9-Serie 3W 5W 10W UV-Laser: https://www.rfhtech.com/s9-series-3w-5w-10w-uv-laser_p9.html 

355-nm-Ultraviolett-Nanosekundenlaser, kurze Wellenlänge, hohe Materialabsorptionsrate, hohe Einzelphotonenenergie, Energiekonzentration, schmale Impulsbreite (25 ns), geringe Wärmeentwicklung bei der Verarbeitung von Polymermaterialien, kleine Wärmeeinflusszone, kann als „kalt“ angesehen werden Die Verarbeitung kann die Schädigung von Polymermaterialien durch thermische Energie reduzieren, die Erzeugung lokaler Mikrorisse und Rückstände effektiv reduzieren und leicht Kanäle mit hoher Ebenheit erhalten Darüber hinaus ist die Strahlqualität hoch (M2 < 1,2) und leicht zu fokussieren. Ein zuverlässiger Schutz kann erreicht werden.